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2022-07-27

NORDESTE AND THE GRADUATE SCHOOL OF DECISION SCIENCE AND TECHNOLOGY, THE UNIVERSITY OF TOKUSHIMA BEGIN JOINT RESEARCH AIMED AT ANALYZING THE ANTI-AGING EFFECTS OF NMN AND ITS MECHANISM.

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Nordeste Corporation and the Graduate School of Decision Science and Technology, The University of Tokushima are pleased to announce the start of joint research on the anti-aging activity of NMN and analysis of its mechanism.

Nordeste The University of Tokushima Graduate School of Decision Science and Technology Regarding joint research

Professor Yoshihiro Utsu, Graduate School of Decision Science and Technology, The University of Tokushima, is engaged in drug discovery chemistry of ingredients that are expected to have anti-aging effects as research that will contribute to a super-aging society in which people are said to live for 100 years.

IN RECENT YEARS, NICOTINAMIDE MONONUCLEOTIDE (NMN), WHICH HAS ATTRACTED MUCH ATTENTION AS AN ANTI-AGING COMPONENT, HAS BEEN SHOWN IN VARIOUS STUDIES IN JAPAN AND OVERSEAS TO EXHIBIT ANTI-AGING EFFECTS SUCH AS IMPROVEMENT OF MOTOR AND COGNITIVE FUNCTIONS IN HUMANS AND MICE, BUT ITS MECHANISM OF ACTION IS STILL UNKNOWN. THEREFORE, ELUCIDATING THE MECHANISM OF ACTION OF NMN IN REGULATING THE AGING PROCESS MAY CONTRIBUTE SIGNIFICANTLY TO IMPROVING THE QUALITY OF LIFE (QOL) OF THE ELDERLY.

IN THIS JOINT RESEARCH, WE WILL ANALYZE THE ANTI-AGING ACTIVITY OF NMN USING HUMAN SENESCENT CELLS AND SENESCENT MICE AND ATTEMPT TO ELUCIDATE THE MECHANISM THROUGH THE ANALYSIS OF KEY MARKERS THAT MEASURE FACTORS THAT HAVE A SIGNIFICANT IMPACT ON AGING.

REGARDING NMN IN NORDESTE.

NORDESTE PROVIDES DOMESTICALLY PRODUCED AND HIGH-PURITY NMN POWDER. WE CONTRIBUTE TO THE FUTURE OF HEALTH AND MEDICINE THROUGH ACADEMIC QUALITY RAW MATERIALS USED IN VARIOUS MEDICAL AND RESEARCH INSTITUTIONS.

Professor Yoshihiro Utsu, Graduate School of Decision Science and Technology, The University of Tokushima, comments

Unraveling the mechanisms of aging and taking countermeasures has been a major part of our research agenda in recent years.
We hope that our approach from our knowledge of anti-aging research using high quality Nordeste NMN will leave new discoveries in the ever-evolving anti-aging research.

Tomotaka Abe, Representative Director of Nordeste Inc.

PROVIDING HIGH-PURITY RAW MATERIALS IS OUR AREA OF EXPERTISE. WE HOPE THAT THIS RESEARCH WITH PROFESSOR UTO, A LEADER IN INDUSTRY-ACADEMIA COLLABORATION IN DRUG DISCOVERY, WILL ELUCIDATE THE SUPERIOR ANTI-AGING EFFECTS OF NMN AND CONTRIBUTE TO ANTI-AGING RESEARCH.

Professor Profile

Name: Yoshihiro Uto

Biography:

  • 1997 RESEARCH FELLOW OF THE JAPAN SOCIETY FOR THE PROMOTION OF SCIENCE (PD)
  • 1998 Research Assistant, Faculty of Engineering, The University of Tokushima
  • 2006 Associate Professor, Faculty of Socio-Techno Science, The University of Tokushima
  • 2014 Professor, Faculty of Socio-Techno Science, The University of Tokushima
  • 2017 Professor, Graduate School of Decision Science and Technology, The University of Tokushima
  • 2019 Professor, Faculty of Industry, The University of Tokushima (concurrent position) To present

Research Field: Drug Discovery Chemistry

Awards:

  • 2004 5th International Association for Research on Sensitization of Cancer Therapy Research Incentive Award (International Association for Research on Sensitization of Cancer Therapy)
  • 2005 THE 5TH AOB RESEARCH ASSOCIATION ENCOURAGEMENT AWARD (AOB RESEARCH ASSOCIATION)
  • 2006 THE TEACHER OF THE YEAR (COLLEGE OF ENGINEERING)
  • 2007 Award for Academic Encouragement, The Free Radical Society of Japan, Inc.
  • 2012 Best Presentation Award for Young Speaker at Engineering Festival (Graduate School of Socio-Techno Science)
  • 2013 Faculty Excellence in Engineering (College of Engineering)
  • 2017 59th Annual Society for Comparative and Integrative Medicine Conference Award (Society for Comparative and Integrative Medicine)
  • 2018 Kangaku Award (Kangaku Foundation)

Organization

  • Nordeste Corporation
  • Head Office: 3-5-8 Sekihara, Adachi-ku, Tokyo
  • MARUNOUCHI OFFICE: MARUNOUCHI NIJUBASHI BUILDING 2F, 3-2-3 MARUNOUCHI, CHIYODA-KU, TOKYO
  • Established: December 1984
  • Representative Director: Tomotaka Abe
  • Capital: 10 million yen
  • URL: https://www.nordeste.co.jp/

Faculty of Bioresources and Bioindustry, The University of Tokushima

The Faculty of Bioresource Science and Industry, established in April 2016 as the first new faculty at the University of Tokushima in 30 years, is the first faculty in Japan to study health science, food science, and agri-science based on biotechnology, and to utilize these technologies across the board. By cultivating a wide range of knowledge and perspectives, we will discover new market needs in the fields of food, medicine, agriculture, forestry, and fisheries, and create new industries that go beyond conventional thinking, thereby contributing to the development of local economies through the use of biological resources.

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