Moisturized skin.

Abe Yoando Pharmaceuticals, derived from the latest research based onits owntheory, developed a serum and gel containing NMN.
Luxuriously formulated withJapan's ^first*1 liposomal NMN,three types of human stem cell culture ^fluid*2, seven types of functional ^peptides*3 and more.
The serum andmultifunctional gel, formulated with a perfect balance of 13 leading ingredients
will leadour skininto an unprecedented realm.
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*1 Survey title: "Survey on NMN Cosmetics" (surveyed by TPC Marketing Research Co., Ltd.) - Survey targets: 1. NMN-containing cosmetics listed on "@cosme" 2. NMN-containing cosmetics sold on "Rakuten Ichiba," "Amazon" and "Yahoo! NMN-containing cosmetics sold through any of the other MLM channels・Survey period: April 1-20, 2022
*2 Human bone marrow stem cell-acclimated culture medium (skin conditioning agent), human fibroblast-acclimated culture medium (skin conditioning agent), human amniotic fluid cell-acclimated culture medium (skin conditioning agent)
*3 Nicotinoyl hexapeptide 44 (skin protective agent), Synthetic human recombinant polypeptide 31 (skin conditioning agent), Human recombinant polypeptide 67 (skin conditioning agent) (skin conditioning agent), human recombinant oligopeptide 1 (skin conditioning agent), synthetic human recombinant polypeptide 64 (skin conditioning agent), synthetic human recombinant polypeptide 16 (skin protective agent)

lose (a match)

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soft peeling

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Moisturize and provide

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NMN SERUM

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Moisturizer, mask, Lift-up

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NMN Multifunctional Gel & Massage Tools

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Learn more about our products

NMN 13 SERIES

NMN 13 Serum
Product Details
NMN 13 Serum
THIS LIPOSOMAL SERUM IS A COMBINATION OF NMN, HUMAN STEM CELL CULTURE FLUID, AND FUNCTIONAL PEPTIDES, AND ITS 13 INGREDIENTS LEAD TO BOUNCY, FRESH SKIN.
Contents
‍30mL
NMN ratio
‍1x
Single Item Price
12,540 yen (including tax)
fixed price
11,913 yen (including tax)
Ingredient name
Water, glycerin, BG, nicotinamide mononucleotide, nicotinoyl hexapeptide 44, human bone marrow stem cell acclimation culture medium, human fibroblast acclimation culture medium, human amniotic cell acclimation culture medium, synthetic human recombinant polypeptide 31, human recombinant polypeptide 67, human recombinant polypeptide 66, synthetic human recombinant oligopeptide 1, synthetic human recombinant polypeptide 64, α-arbutin, sodium hyaluronate, alanthanine ポリペプチドー６６、ヒト遺伝子組換オリゴペプチドー１、合成ヒト遺伝子組換ポリペプチドー６４、合成ヒト遺伝子組換ポリペプチドー１６、αーアルブチン、ヒアルロン酸Ｎａ、アラントイン、グリチルリチン酸２Ｋ、ユキノシタエキス、（アクリレーツ／アクリル酸アルキル（Ｃ１０ (C10-30) crosspolymer, button extract, dimethylaminoethanol tartrate, ascorbyl Mg phosphate, pyridoxine HCl, cholesterol, kuzu root extract, 3N ascorbyl phosphate palmitate, palmitic acid, sodium ascorbyl phosphate, EDTA-2 Na, citric acid, polysorbate 80, hydrogenated lecithin, hydrogenated phosphatidylcholine, carnosine, xanthan gum, carrageenan, lauryl betaine, sucrose, mallow extract, sodium chitosanlauramide hydroxypropyl sulfonate, soybean oil, ethanol, phenoxyethanol, 1,2-hexanediol, PEG-40 hydrogenated castor oil, tocopherol acetate, lecithin, fragrance
usage rules
Morning and night, after washing your face, take a dropper of 10 yen size and apply to entire face. If dryness is a concern, we recommend applying a layer of the product.
Precautions for use
Use with caution to avoid any skin problems. We recommend a patch test on an inconspicuous area of your skin beforehand. If the cosmetics do not agree with your skin, i.e., in the following cases, please discontinue use. Continued use of cosmetics may aggravate symptoms, so we recommend consulting a dermatologist or other health care professional.
(1) If you notice redness, swelling, itching, irritation, color loss (such as vitiligo), dark spots, or other abnormalities during use.
(2) If any of the above-mentioned abnormalities appear on the skin exposed to direct sunlight after use.
Do not use on areas with scars, rashes, or other abnormalities.
Avoid contact with eyes. If it does get into your eyes, rinse immediately with water or lukewarm water.

NMN 13 Jelly
Product Details
NMN 13 Jelly
MULTIFUNCTIONAL GEL CONTAINING 13 INGREDIENTS INCLUDING LIPOSOMIZED NMN. COMBINED WITH THE MASSAGE TOOL "CONTOURER", IT GIVES AN UPWARD IMPRESSION.
Contents
‍30g
NMN ratio
‍1x
Single Item Price　
12,540 yen (including tax)
fixed price　　
11,913 yen (including tax)
Ingredient name
Water, BG, glycerin, (PEG-240/decyltetradeceth-20/HDI) copolymer, nicotinamide mononucleotide, nicotinoyl hexapeptide 44, human bone marrow stem cell acculturation medium, human fibroblast acculturation medium, human amniotic fluid Cell acclimation culture medium, synthetic human recombinant polypeptide 31, human recombinant polypeptide 67, human recombinant polypeptide 66, human recombinant oligopeptide 1, synthetic human recombinant polypeptide 64, synthetic human recombinant polypeptide 16, α-arbutin, hyaluronic acid Na, allantoin, 2K glycyrrhizate, (acrylates/alkyl acrylate (C10-30)) crosspolymer, button extract, dimethylaminoethanol tartrate, ascorbyl Mg phosphate, pyridoxine HCl, cholesterol, kuzu root extract, Ascorbyl phosphate trisodium palmitate, palmitic acid, sodium ascorbyl phosphate, EDTA-2Na, citric acid, polysorbate 80, hydrogenated lecithin, hydrogenated phosphatidylcholine, carnosine, lauryl betaine, mallow extract, chitosan lauramide hydroxypropyl sulfonate Na Soybean oil, 1,2-hexanediol, panthenol, arginine, tocopherol, K laurate, phenoxyethanol, PPG-4 cetesu-20, tocopherol acetate, lecithin, fragrance
usage rules
After washing your face, take a cherry-sized amount and massage it over your face. We recommend applying a layer of the product to areas where you are concerned about impressions.
Precautions for use
Use with caution to avoid any skin problems. We recommend a patch test on an inconspicuous area of your skin beforehand. If the cosmetics do not agree with your skin, i.e., in the following cases, please discontinue use. Continued use of cosmetics may aggravate symptoms, so we recommend consulting a dermatologist or other health care professional.
(1) If you notice redness, swelling, itching, irritation, color loss (such as vitiligo), dark spots, or other abnormalities during use.
(2) If any of the above-mentioned abnormalities appear on the skin exposed to direct sunlight after use.
Do not use on areas with scars, rashes, or other abnormalities.
Avoid contact with eyes. If it does get into your eyes, rinse immediately with water or lukewarm water.

NMN 13 Serum for Pro
Product Details
NMN 13 Serum for Pro
Sold at clinics and salons
RICH MODEL THAT PROVIDES SALON-LEVEL CARE AT HOME. CONTAINS TWICE AS MUCH LIPOSOMAL NMN AS THE STANDARD VERSION. RECOMMENDED FOR USE WITH A FACIAL MACHINE.
Contents
‍30mL
NMN ratio
‍2x
Single Item Price
45,980 yen (including tax)
fixed price　　
43,681 yen (including tax)
Ingredient name
Water, glycerin, BG, nicotinamide mononucleotide, nicotinoyl hexapeptide 44, human bone marrow stem cell acclimation culture medium, human fibroblast acclimation culture medium, human amniotic cell acclimation culture medium, synthetic human recombinant polypeptide 31, human recombinant polypeptide 67, human recombinant polypeptide 66, synthetic human recombinant oligopeptide 1, synthetic human recombinant polypeptide 64, α-arbutin, sodium hyaluronate, alanthanine ポリペプチドー６６、ヒト遺伝子組換オリゴペプチドー１、合成ヒト遺伝子組換ポリペプチドー６４、合成ヒト遺伝子組換ポリペプチドー１６、αーアルブチン、ヒアルロン酸Ｎａ、アラントイン、グリチルリチン酸２Ｋ、ユキノシタエキス、（アクリレーツ／アクリル酸アルキル（Ｃ１０ (C10-30) crosspolymer, button extract, dimethylaminoethanol tartrate, ascorbyl Mg phosphate, pyridoxine HCl, cholesterol, kuzu root extract, 3N ascorbyl phosphate palmitate, palmitic acid, sodium ascorbyl phosphate, EDTA-2 Na, citric acid, polysorbate 80, hydrogenated lecithin, hydrogenated phosphatidylcholine, carnosine, xanthan gum, carrageenan, lauryl betaine, sucrose, mallow extract, sodium chitosanlauramide hydroxypropyl sulfonate, soybean oil, ethanol, phenoxyethanol, 1,2-hexanediol, PEG-40 hydrogenated castor oil, tocopherol acetate, lecithin, fragrance
usage rules
Morning and night, after washing your face, take a dropper of 10 yen size and apply to entire face. If dryness is a concern, we recommend applying a layer of the product.
Precautions for use
Use with caution to avoid any skin problems. We recommend a patch test on an inconspicuous area of your skin beforehand. If the cosmetics do not agree with your skin, i.e., in the following cases, please discontinue use. Continued use of cosmetics may aggravate symptoms, so we recommend consulting a dermatologist or other health care professional.
(1) If you notice redness, swelling, itching, irritation, color loss (such as vitiligo), dark spots, or other abnormalities during use.
(2) If any of the above-mentioned abnormalities appear on the skin exposed to direct sunlight after use.
Do not use on areas with scars, rashes, or other abnormalities.
Avoid contact with eyes. If it does get into your eyes, rinse immediately with water or lukewarm water.

Support Items

SkinRefiner

Peeling gel that leads to clear and soft skin

5g x 4pac (4 times)

Single item price 2,980 yen (tax included)

Product Details

set item

NMN SKIN CARE BOOSTER

NMN 13 Serum + SkinRefiner

WEEKLY SOFT PEELS TO ENHANCE PENETRATION** OF NMN SERUMS.

Product Details

NMN DUAL CARE

NMN 13 Serum + Yoando NMN 18000 Beauty

Skin care x inner care for a youthful appearance from the inside and out.

Product Details

*Nicotinamide mononucleotide (moisturizing)
**To stratum corneum

Quality
Management

Quality Assurance System
Pursuit of Safety and Results

WE AT ABE YOANDO PHARMACEUTICALS CONDUCT VARIOUS INSPECTIONS AND TESTS TO ENSURE THAT WE ALWAYS DELIVER THE BEST NMN. WE WILL CONTINUE TO REDUCE EACH AND EVERY POSSIBLE RISK FROM THE TIME OF DELIVERY UNTIL AFTERWARDS.

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raw materials

USES HIGH-PURITY 99.9%* NMN

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manufacture

Special "low-toxin manufacturing method" ensures safety of intravenous drug formulation standards.

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IN-HOUSE PRODUCTION OF "HEAT-RESISTANT" NMN RAW MATERIALS

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MANUFACTURED IN A PLANT THAT MEETS GQP, GVP, AND W STANDARDS

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examination

Perform lot-by-lot raw material authenticity testing

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Safety inspections conducted (acute toxicity testing, radioactivity testing)

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NMN*¹は水溶液を肌から与えると、 NMN量が100倍に増加したという研究結果も。

*1：ニコチンアミドモノヌクレオチド（保湿）
[参考]著者：服部研之（慶応大薬）、青柳良平（慶応大薬）、伊達朗（P&Gジャパン）、阿部芳廣（慶応大薬）、田村悦臣（慶応大薬）、”NAD生合成の前駆体・ニコチン酸アミドモノヌクレオチド（NMN）のヒト皮膚表皮の分化に及ぼす影響”論文.2013年

Boosting Beauty Benefits
Liposome Technology

美容成分を、人の肌と親和性が高い、リン脂質でできた何層にもなるカプセルの中に閉じ込めて、肌のすみずみ*へ届ける技術です。
リポソーム化することで、一部の劣化しやすい美容成分を、配合したての新鮮な状態でお肌のすみずみへ浸透*させることが可能になり、より成分の魅力をご体感いただけるようになります。
* 角層まで

Hydrophilic part Active ingredient Hydrophobic part

13 beauty ingredients approach
glowing, radiant skin
"All-Effects Formulation®"

NMN^*の魅力を存分に引き出すために、３種のヒト幹細胞培養液^**、7種のペプチド^***、2種のサポート成分を配合。最新の研究に基づいたNMNを含む、13成分の絶妙配合こそが、NMN 13シリーズ独自の「オールエフェクト処方®」※。若々しい印象の肌へのステップをサポートしています。
^* ニコチンアミドモノヌクレオチド（保湿剤）
^** ヒト骨髄幹細胞順化培養液（皮膚コンディショニング剤）、ヒト線維芽細胞順化培養液（皮膚コンディショニング剤）、ヒト羊水細胞順化培養液（皮膚コンディショニング剤）
‍^*** ニコチノイルヘキサペプチドー４４（皮膚保護剤）、合成ヒト遺伝子組換ポリペプチドー３１（皮膚コンディショニング剤）、ヒト遺伝子組換ポリペプチドー６７（皮膚コンディショニング剤）、ヒト遺伝子組換ポリペプチドー６６（皮膚コンディショニング剤）、ヒト遺伝子組換オリゴペプチドー１（皮膚コンディショニング剤）、合成ヒト遺伝子組換ポリペプチドー６４（皮膚コンディショニング剤）、合成ヒト遺伝子組換ポリペプチドー１６（皮膚保護剤）
※オールエフェクト処方®は阿部養庵堂薬品の登録商標です。(肌を整える・肌をひきしめる・皮膚の水分、油分を補い保つ・皮膚の柔軟性を保つ・肌にはりを与える　等の多機能アプローチ）

Hydrophilic part Beauty ingredient Hydrophobic part

13 Ingredients

『NMN 13 セラム』は、日本初^*のリポソーム化^**NMN^***をサポートする成分にもこだわりました。アミノ酸を豊富に含むペプチド、美容科学の世界で注目を浴び続けている幹細胞培養液エキスなどもリポソーム化したことで、13の成分があなたの肌をしっかりサポートします。

^* 調査名：「NMN化粧品に関する調査」（TPCマーケティングリサーチ㈱調べ）・調査対象：　1.「@cosme」に記載のあるNMN配合化粧品2.「楽天市場」「Amazon」「Yahoo!ショッピング」で販売されているNMN配合化粧品3.その他MLMチャネルで販売されているNMN配合化粧品のいずれかに該当するもの・調査期間：2022年4月1日～20日
^**酒石酸ジメチルアミノエタノール（DMAE）、アラントインを除く。
^*** ニコチンアミドモノヌクレオチド（保湿剤）

NMN

A rare ingredient that is gaining attention as a key to anti-aging care*.　 _{*Age-appropriate care}

1NMN [ nicotinamide mononucleotide ] (Moisturizer)

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Gene-like" bio-based peptides

Human-derived peptides that support skin conditioning and skin beautification.

2 Human recombinant polypeptide-66 (skin conditioning agent)

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3 Human recombinant polypeptide-67 (skin conditioning agent)

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4 Nicotinoyl hexapeptide-44 [propyn] (skin protectant)

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5 Synthetic human recombinant polypeptide-64 [aquaporin] (skin conditioning agent)

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6 Human recombinant polypeptide-1 (skin conditioning agent)

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7 Synthetic human recombinant polypeptide-16 (skin protectant)

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8 Synthetic human recombinant polypeptide-31 (skin conditioning agent)

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Human stem cell acclimatization culture medium

Human-derived with high affinity to skin. Luxurious rare ingredients used in the field of beauty science.

9 Human amniotic fluid cell culture medium (skin conditioning agent)

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10 Human bone marrow stem cell acculturation medium (skin conditioning agent)

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11 Human fibroblast acculturation medium (skin conditioning agent)

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Synergy Components

IT MAXIMIZES THE ATTRACTIVENESS OF NMN AND BRINGS ABOUT A SYNERGISTIC EFFECT.

12 Dimethylaminoethanol tartrate [DMAE] (emollient)

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13 Allantoin (skin conditioning agent)

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Concept

医療現場シェア80％³を誇る
高品質NMN¹原料を
リポソームカプセルに閉じ込めた「塗るNMN*¹点滴」

IN THE COURSE OF ABE YOANDO PHARMACEUTICAL'S DAY AND NIGHT RESEARCH, WE DISCOVERED THAT TO EFFECTIVELY TREAT AGING, IT IS NECESSARY TO ATTACK SEVEN TARGETS AT THE SAME TIME. THE "NMN13 SERIES" IS A SKINCARE LINE DEVELOPED BASED ON THIS RESEARCH AND THEORY AND EQUIPPED WITH HUMAN SKIN-FRIENDLY TECHNOLOGY.

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Technology

Japan's ^first*1
Liposomal NMN formula
Serum & multifunctional gel

Synergistic ingredients including NMN, the main ingredient, and three types of human stem cell culture fluid are all^{liposomized*2.}
Reaches ^Deeper*313 ingredients work omnidirectionally on the sleeping beauty skin switch to lead to glowing skin full of freshness.

*1 Survey title: "Survey on NMN Cosmetics" (TPC Marketing Research Co., Ltd.); survey targets: 1. NMN-based cosmetics listed on "@cosme," 2. NMN-based cosmetics sold on Rakuten Ichiba, Amazon, and Yahoo! 3. Cosmetics containing NMN sold through other MLM channels.
*2 Excluding dimethylaminoethanol tartrate (DMAE) and allantoin.　*3 To stratum corneum

Boosting Beauty Benefits
Liposome Technology

This is a technology that ensures the delivery of beauty ingredients to the skin by trapping them in multi-layered capsules made of phospholipids, which have a high affinity with the human skin.
Liposomization enables some easily degraded beauty ingredients to penetrate* into the skin in their freshly blended state, making it possible for the ingredients to be more appealing to the skin.

* Down to the stratum corneum

Take a closer look

13 beauty ingredients approach
glowing, radiant skin
"All-Effects Formulation®"

To bring out the full appeal of NMN, three types of human stem cell culture fluid*, seven types of peptides**, and two types of supportive ingredients are combined. The exquisite combination of 13 ingredients, including NMN based on the latest research, is the unique "All-Effects Formulation®"** of the NMN 13 series. It supports the steps to younger-looking skin.

** Human bone marrow stem cell acclimatized culture medium (skin conditioning agent), human fibroblast acclimatized culture medium (skin conditioning agent), human amniotic fluid cell acclimatized culture medium (skin conditioning agent)** Nicotinoyl hexapeptide 44 (skin protective agent), synthetic human recombinant polypeptide 31 (skin コンディショニング剤）、ヒト遺伝子組換ポリペプチドー６７（皮膚コンディショニング剤）、ヒト遺伝子組換ポリペプチドー６６（皮膚コンディショニング剤）、ヒト遺伝子組換オリゴペプチドー１（皮膚コンディショニング剤）、合成ヒト遺伝子組換ポリペプチドー６４（皮膚 conditioning agent), Synthetic human recombinant polypeptide 16 (skin protective agent)
*All Effects Formulation® is a registered trademark of Nordeste. (Multi-functional approach to skin conditioning, skin firming, supplementing and maintaining skin moisture and oil, maintaining skin flexibility, giving skin elasticity, etc.)

EXPECTATIONS FOR NMN SKIN

NMN is also very well absorbed into the skin*, and research has shown** that when NMN solution is applied to the skin, NMN is 100 times higher and coenzymes are 4 times higher. Enjoy the NMN experience from your skin.

** Down to the stratum corneum** [Reference] Authors: Kenyuki Hattori (Keio Univ.), Ryohei Aoyagi (Keio Univ.), Akira Date (P&G Japan), Yoshihiro Abe (Keio Univ.), Etsuomi Tamura (Keio Univ.). "Effect of nicotinic acid amide mononucleotide (NMN), a precursor of NAD biosynthesis, on the differentiation of human skin epidermis," Article. 2013