ヒト研究から誕生した、
誰よりも若々しさを追求したい方のための
日本初*リポソーム化NMN** 配合美容液
Abe Yoando Pharmaceuticals, derived from the latest research based onits owntheory, developed a serum and gel containing NMN.
Luxuriously formulated withJapan's first*1 liposomal NMN,three types of human stem cell culture fluid*2 , seven types of functional peptides*3 and more.
The serum andmultifunctional gel, formulated with a perfect balance of 13 leading ingredients
will leadour skininto an unprecedented realm.
*1 Survey title: "Survey on NMN Cosmetics" (surveyed by TPC Marketing Research Co., Ltd.) - Survey targets: 1. NMN-containing cosmetics listed on "@cosme" 2. NMN-containing cosmetics sold on "Rakuten Ichiba," "Amazon" and "Yahoo! NMN-containing cosmetics sold through any of the other MLM channels・Survey period: April 1-20, 2022
*2 Human bone marrow stem cell-acclimated culture medium (skin conditioning agent), human fibroblast-acclimated culture medium (skin conditioning agent), human amniotic fluid cell-acclimated culture medium (skin conditioning agent)
*3 Nicotinoyl hexapeptide 44 (skin protective agent), Synthetic human recombinant polypeptide 31 (skin conditioning agent), Human recombinant polypeptide 67 (skin conditioning agent) (skin conditioning agent), human recombinant oligopeptide 1 (skin conditioning agent), synthetic human recombinant polypeptide 64 (skin conditioning agent), synthetic human recombinant polypeptide 16 (skin protective agent)
lose (a match)
[
soft peeling
]
Moisturize and provide
[
NMN SERUM
]
Moisturizer, mask, Lift-up
[
NMN Multifunctional Gel & Massage Tools
]
NMN SKIN CARE BOOSTER
*Nicotinamide mononucleotide (moisturizing)
**To stratum corneum
WE AT ABE YOANDO PHARMACEUTICALS CONDUCT VARIOUS INSPECTIONS AND TESTS TO ENSURE THAT WE ALWAYS DELIVER THE BEST NMN. WE WILL CONTINUE TO REDUCE EACH AND EVERY POSSIBLE RISK FROM THE TIME OF DELIVERY UNTIL AFTERWARDS.
NMN*は経口摂取の場合、生命維持との関わりが強いところから順番に使われていきます。そのため、お肌などの外見にも優先的に届けられるよう『NMN 13 Serum』は誕生しました。
* ニコチンアミドモノヌクレオチド(保湿剤)
**・調査対象:①美容外科、②整形外科、③形成外科、④⽪膚科のいずれかの登録がある医院・クリニックのうち、 NMN点滴サービスを提供している医院・クリニック。・「保険医療機関・保険薬局の指定等⼀覧」に記載のある医院・クリニックのうち、NMN点滴を導⼊している医院・クリニックは全国で198件あり、そのうち当社のNMNサプリメントと同原料を採⽤している医院・クリニックは157件。(2022年10月7日 TPCマーケティングリサーチ株式会社調べ)
NMN*1は水溶液を肌から与えると、 NMN量が100倍に増加したという研究結果も。
*1:ニコチンアミドモノヌクレオチド(保湿)
[参考]著者:服部研之(慶応大薬)、青柳良平(慶応大薬)、伊達朗(P&Gジャパン)、阿部芳廣(慶応大薬)、田村悦臣(慶応大薬)、”NAD生合成の前駆体・ニコチン酸アミドモノヌクレオチド(NMN)のヒト皮膚表皮の分化に及ぼす影響”論文.2013年
美容成分を、人の肌と親和性が高い、リン脂質でできた何層にもなるカプセルの中に閉じ込めて、肌のすみずみ*へ届ける技術です。
リポソーム化することで、一部の劣化しやすい美容成分を、配合したての新鮮な状態でお肌のすみずみへ浸透*させることが可能になり、より成分の魅力をご体感いただけるようになります。
* 角層まで
NMN*の魅力を存分に引き出すために、3種のヒト幹細胞培養液**、7種のペプチド***、2種のサポート成分を配合。最新の研究に基づいたNMNを含む、13成分の絶妙配合こそが、NMN 13シリーズ独自の「オールエフェクト処方®」※。若々しい印象の肌へのステップをサポートしています。
* ニコチンアミドモノヌクレオチド(保湿剤)
** ヒト骨髄幹細胞順化培養液(皮膚コンディショニング剤)、ヒト線維芽細胞順化培養液(皮膚コンディショニング剤)、ヒト羊水細胞順化培養液(皮膚コンディショニング剤)
*** ニコチノイルヘキサペプチドー44(皮膚保護剤)、合成ヒト遺伝子組換ポリペプチドー31(皮膚コンディショニング剤)、ヒト遺伝子組換ポリペプチドー67(皮膚コンディショニング剤)、ヒト遺伝子組換ポリペプチドー66(皮膚コンディショニング剤)、ヒト遺伝子組換オリゴペプチドー1(皮膚コンディショニング剤)、合成ヒト遺伝子組換ポリペプチドー64(皮膚コンディショニング剤)、合成ヒト遺伝子組換ポリペプチドー16(皮膚保護剤)
※オールエフェクト処方®は阿部養庵堂薬品の登録商標です。(肌を整える・肌をひきしめる・皮膚の水分、油分を補い保つ・皮膚の柔軟性を保つ・肌にはりを与える 等の多機能アプローチ)
『NMN 13 セラム』は、日本初*のリポソーム化**NMN***をサポートする成分にもこだわりました。アミノ酸を豊富に含むペプチド、美容科学の世界で注目を浴び続けている幹細胞培養液エキスなどもリポソーム化したことで、13の成分があなたの肌をしっかりサポートします。
* 調査名:「NMN化粧品に関する調査」(TPCマーケティングリサーチ㈱調べ)・調査対象: 1.「@cosme」に記載のあるNMN配合化粧品2.「楽天市場」「Amazon」「Yahoo!ショッピング」で販売されているNMN配合化粧品3.その他MLMチャネルで販売されているNMN配合化粧品のいずれかに該当するもの・調査期間:2022年4月1日~20日
** 酒石酸ジメチルアミノエタノール(DMAE)、アラントインを除く。
*** ニコチンアミドモノヌクレオチド(保湿剤)
A rare ingredient that is gaining attention as a key to anti-aging care*. *Age-appropriate care
Human-derived peptides that support skin conditioning and skin beautification.
Human-derived with high affinity to skin. Luxurious rare ingredients used in the field of beauty science.
IT MAXIMIZES THE ATTRACTIVENESS OF NMN AND BRINGS ABOUT A SYNERGISTIC EFFECT.
IN THE COURSE OF ABE YOANDO PHARMACEUTICAL'S DAY AND NIGHT RESEARCH, WE DISCOVERED THAT TO EFFECTIVELY TREAT AGING, IT IS NECESSARY TO ATTACK SEVEN TARGETS AT THE SAME TIME. THE "NMN13 SERIES" IS A SKINCARE LINE DEVELOPED BASED ON THIS RESEARCH AND THEORY AND EQUIPPED WITH HUMAN SKIN-FRIENDLY TECHNOLOGY.
The development of the NMN serum began when we first encountered NMN and fell in love with its wonderful properties.
NMN is wonderful when taken, but when we learned that it also has a positive effect when applied to the skin, we repeated trial and error in order to perfect it as a skincare product at any cost.
Since we use high-quality NMN raw materials, we were also particular about the support ingredients surrounding NMN.
We have created an "All-Effect Formulation®" serum by exquisitely blending rare human amniotic stem cell purified culture fluid, seven types of peptides, and other ingredients unique to our company, so that you can fully experience the appeal of NMN.
We hope you will experience it for yourself.
We want to provide a formulation that is easy on your skin because you use it every day. With this in mind, we do not use parabens, mineral oil, synthetic colorants, synthetic fragrances, talc, silicone, or vergaptene.
Synergistic ingredients including NMN, the main ingredient, and three types of human stem cell culture fluid are allliposomized*2.
Reaches Deeper*3 13 ingredients work omnidirectionally on the sleeping beauty skin switch to lead to glowing skin full of freshness.
*1 Survey title: "Survey on NMN Cosmetics" (TPC Marketing Research Co., Ltd.); survey targets: 1. NMN-based cosmetics listed on "@cosme," 2. NMN-based cosmetics sold on Rakuten Ichiba, Amazon, and Yahoo! 3. Cosmetics containing NMN sold through other MLM channels.
*2 Excluding dimethylaminoethanol tartrate (DMAE) and allantoin. *3 To stratum corneum
This is a technology that ensures the delivery of beauty ingredients to the skin by trapping them in multi-layered capsules made of phospholipids, which have a high affinity with the human skin.
Liposomization enables some easily degraded beauty ingredients to penetrate* into the skin in their freshly blended state, making it possible for the ingredients to be more appealing to the skin.
* Down to the stratum corneum
To bring out the full appeal of NMN, three types of human stem cell culture fluid*, seven types of peptides**, and two types of supportive ingredients are combined. The exquisite combination of 13 ingredients, including NMN based on the latest research, is the unique "All-Effects Formulation®"** of the NMN 13 series. It supports the steps to younger-looking skin.
** Human bone marrow stem cell acclimatized culture medium (skin conditioning agent), human fibroblast acclimatized culture medium (skin conditioning agent), human amniotic fluid cell acclimatized culture medium (skin conditioning agent)** Nicotinoyl hexapeptide 44 (skin protective agent), synthetic human recombinant polypeptide 31 (skin コンディショニング剤)、ヒト遺伝子組換ポリペプチドー67(皮膚コンディショニング剤)、ヒト遺伝子組換ポリペプチドー66(皮膚コンディショニング剤)、ヒト遺伝子組換オリゴペプチドー1(皮膚コンディショニング剤)、合成ヒト遺伝子組換ポリペプチドー64(皮膚 conditioning agent), Synthetic human recombinant polypeptide 16 (skin protective agent)
*All Effects Formulation® is a registered trademark of Nordeste. (Multi-functional approach to skin conditioning, skin firming, supplementing and maintaining skin moisture and oil, maintaining skin flexibility, giving skin elasticity, etc.)
NMN is also very well absorbed into the skin*, and research has shown** that when NMN solution is applied to the skin, NMN is 100 times higher and coenzymes are 4 times higher. Enjoy the NMN experience from your skin.
** Down to the stratum corneum** [Reference] Authors: Kenyuki Hattori (Keio Univ.), Ryohei Aoyagi (Keio Univ.), Akira Date (P&G Japan), Yoshihiro Abe (Keio Univ.), Etsuomi Tamura (Keio Univ.). "Effect of nicotinic acid amide mononucleotide (NMN), a precursor of NAD biosynthesis, on the differentiation of human skin epidermis," Article. 2013
NMN 13 Serum" and "NMN 13 Gelée" are the first liposomalized products in Japan*. Liposomalized peptides rich in amino acids and stem cell culture fluid extract, which continues to attract attention in the world of beauty science, are among the 13 ingredients that provide firm support for your skin.
* Survey title: "Survey on NMN Cosmetics" (surveyed by TPC Marketing Research Co., Ltd.) - Targets of the survey: 1. NMN-based cosmetics listed on "@cosme" 2. NMN-based cosmetics sold on "Rakuten Ichiba," "Amazon" and "Yahoo! Cosmetics containing NMN sold on "Rakuten Ichiba", "Amazon", and "Yahoo! Shopping" 3. Cosmetics containing NMN sold through other MLM channels.
** Excluding dimethylaminoethanol tartrate (DMAE) and allantoin.
A rare ingredient that is gaining attention as a key to anti-aging care*. *Age-appropriate care
Human-derived peptides that support skin conditioning and skin beautification.
Human-derived with high affinity to skin. Luxurious rare ingredients used in the field of beauty science.
IT MAXIMIZES THE ATTRACTIVENESS OF NMN AND BRINGS ABOUT A SYNERGISTIC EFFECT.
TO FULLY APPRECIATE THE APPEAL OF 13 KEY INGREDIENTS, INCLUDING JAPAN'S FIRST LIPOSOMAL NMN, HUMAN STEM CELL CULTURE FLUID, FUNCTIONAL PEPTIDES, AND MORE. WE WILL TELL YOU HOW TO USE THEM TO MAXIMIZE THE APPEAL OF YOUR SKIN.
リポソーム技術で、NMN*1を肌のすみずみへ浸透*2。
人に会うのが楽しくなる。お肌の悩みから解放されたい方のNMN美容液。
*1ニコチンアミドモノヌクレオチド(保湿) *2角層まで
*ニコチンアミドモノヌクレオチド(保湿)
**ニコチノイルヘキサペプチドー44、合成ヒト遺伝子組換ポリペプチドー16(皮膚保護剤)、合成ヒト遺伝子組換ポリペプチドー31、ヒト遺伝子組換ポリペプチドー67、ヒト遺伝子組換ポリペプチドー66、ヒト遺伝子組換オリゴペプチドー1、合成ヒト遺伝子組換ポリペプチドー64(皮膚コンディショニング剤)
***ヒト羊水細胞順化培養液、ヒト骨髄幹細胞順化培養液、ヒト線維芽細胞順化培養液(皮膚コンディショニング剤)