N-Pro Med®︎", No.1 share of NMN reagent raw materials

Also used in research at the University of Tokyo Faculty of Medicine, Kyoto University Faculty of Medicine, Shimane University Faculty of Medicine, Hyogo Medical University, Tokyo University of Science Faculty of Pharmaceutical Sciences, Shizuoka University, Tokushima University, and Tottori University.
80% share of the medical institution market*, NMN is by far the preferred choice
*Surveyed by TPC Marketing Research Inc.

We offer "N-Pro Med®︎," an NMN research reagent raw material that meets the strict standards required by professionals at medical and research institutions. N-Pro Med®︎" is the only NMN research reagent raw material used in research papers in which the safety and efficacy of intravenous (IV) administration to humans were confirmed*.
*As of September 2022, according to our own research.

caution

The products manufactured by other companies have only the same level of quality standards as food powder raw materials, and we cannot dispel concerns that they do not take the necessary steps for reagents, such as Authenticity, Purity, Stability, and Safety (sterilization process).

NMN REAGENT RAW MATERIAL USED IN THE WORLD'S ONLY RESEARCH PAPER THAT CONFIRMED THE SAFETY AND EFFICACY OF INTRAVENOUS ADMINISTRATION TO HUMANS

N-Pro Med®︎" has been used as a research reagent raw material in the following studies

• Prof. Akinobu Goto and his research group (Hyogo Medical University)

  Article Abstract
  Examines the safety of intravenous administration of 300 mg of NMN. Intravenous NMN administration appears to be safe and beneficial.

  Efficacy
  Safety of intravenous administration of 300 mg of NMN.
  Intravenous NMN administration is considered safe and beneficial.
  ・Improved blood longevity molecule NAD+ level by about 20% (see NAD+ level graph)
  ・Improved sleep quality
  ・Blood fat (TG level) decreased by about 75% (see TG level graph)
  ・Improved TG level may lead to prevention and treatment of fatty liver and diabetes-related diseases
  

  

  TG LEVEL GRAPH

  

  NAD+ LEVEL GRAPH

• The University of Tokyo School of Medicine

  Not disclosed

• Kyoto University Graduate School of Medicine

  RESEARCH TO ELUCIDATE THE EFFECTS OF NMN ON DNA METHYLATION AND ITS MECHANISM OF ACTION

• Shimane University School of Medicine

  RESEARCH ON THE EFFECTS AND MECHANISMS OF NMN ON OXIDATIVE STRESS

• Tokyo University of Science, Faculty of Pharmaceutical Sciences

  RESEARCH ON THE ANTI-FATIGUE EFFECTS OF NMN AND DEMENTIA

• The University of Tokushima

  RESEARCH ON ANTI-AGING ACTIVITY OF NMN USING HUMAN CELLS AND AGING MODEL MICE

• University of Shizuoka

  RESEARCH ON THE EFFECTS AND MECHANISMS OF NMN ON AGE-RELATED MUSCLE ATROPHY AND OBESITY

  
  【Pubmed】
  Nicotinamide mononucleotide induces lipolysis by regulating ATGL expression via the SIRT1-AMPK axis in adipocytes
  ニコチンアミドモノヌクレオチドは、脂肪細胞におけるSIRT1-AMPK軸を介してATGL発現を調節することにより脂肪分解を誘導する
  ‍https://pubmed.ncbi.nlm.nih.gov/37144119/
  ‍https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151261/　(全文）

• Tottori University

  ANTI-AGING EFFECTS OF NMN ON DOGS AND CATS

*Since some research institutions do not disclose their results reports, only those that have permission to publish are listed.

Quality Control System

N-Pro Med®︎" is manufactured and controlled under a strict quality maintenance system.

Authenticity
Quality is controlled by producing NMN from raw materials in Japan.
There are two types of NMN: alpha-NMN and beta-NMN. β-NMN is the one that is produced in the human body and has been confirmed to be safe and useful for humans.
N-Pro Med®︎" is 100% β-NMN*.
*Inspection organization: Japan Food Analysis Center
Test method: Nuclear magnetic resonance spectroscopy‍
P urity
The highest purity of 99.9%* is achieved through a special purification process.
*Inspection organization : Japan Food Inspection
Test method: High performance liquid chromatography
Stability (stability )
Stability quality (thermal decomposition) test*.
*Inspection organization : Nordeste Corporation
Test method: High performance liquid chromatography for NMN decay from 0 to 3 months at 4°C, 25°C, and 40°C, respectively
Safety
Highly safe NMN that can meet the Japanese Pharmacopoeia standard values* (intravenous administration).
*Inspection organization: Japan Food Analysis Center
Test method: Colorimetric method

Ingredient Information

β-Nicotinamide mononucleotide
β-Nicotinamide mononucleotide

β-Nicotinamide mononucleotide is an intermediate metabolite of the coenzyme NAD+, which is present in all living species. N-Pro Med®︎" is a research reagent raw material for purified β-Nicotinamide mononucleotide.
CAS No: 1094-61-7
Chemical formula: C11H15N2O8P
Structural formula: