Product List

Liposome technology penetrates NMN* into every nook and cranny of the skin**.
You will enjoy meeting people. NMN serum for those who want to be free from skin problems.

*Nicotinamide mononucleotide (moisturizing) **to the stratum corneum

*Nicotinamide mononucleotide (moisturizing)
**To stratum corneum

Moisturized skin.

Abe Yoando Pharmaceuticals, derived from the latest research based onits owntheory, developed a serum and gel containing NMN.
Luxuriously formulated withJapan's first*1 liposomal NMN,three types of human stem cell culture fluid*2 , seven types of functional peptides*3 and more.
The serum andmultifunctional gel, formulated with a perfect balance of 13 leading ingredients
will leadour skininto an unprecedented realm.

*1 Survey title: "Survey on NMN Cosmetics" (surveyed by TPC Marketing Research Co., Ltd.) - Survey targets: 1. NMN-containing cosmetics listed on "@cosme" 2. NMN-containing cosmetics sold on "Rakuten Ichiba," "Amazon" and "Yahoo! NMN-containing cosmetics sold through any of the other MLM channels・Survey period: April 1-20, 2022
*2 Human bone marrow stem cell-acclimated culture medium (skin conditioning agent), human fibroblast-acclimated culture medium (skin conditioning agent), human amniotic fluid cell-acclimated culture medium (skin conditioning agent)
*3 Nicotinoyl hexapeptide 44 (skin protective agent), Synthetic human recombinant polypeptide 31 (skin conditioning agent), Human recombinant polypeptide 67 (skin conditioning agent) (skin conditioning agent), human recombinant oligopeptide 1 (skin conditioning agent), synthetic human recombinant polypeptide 64 (skin conditioning agent), synthetic human recombinant polypeptide 16 (skin protective agent)

lose (a match)

soft peeling

]

SkinRefinerSkinRefiner Product Images

Moisturize and provide

NMN SERUM

]

NMN 13 Serum NMN 13 Serum for Pro

Moisturizer, mask, Lift-up

NMN Multifunctional Gel & Massage Tools

]

NMN 13 Jelly ContourerNMN 13 Jelly Product Images
Learn more about our products
NMN 13 SERIES
  • NMN 13 Serum

    NMN 13Serum
    Product Details

    NMN 13 Serum

    THIS LIPOSOMAL SERUM IS A COMBINATION OF NMN, HUMAN STEM CELL CULTURE FLUID, AND FUNCTIONAL PEPTIDES, AND ITS 13 INGREDIENTS LEAD TO BOUNCY, FRESH SKIN.

  • 30mL

    Contents
    ‍30mL

    x1

    NMN ratio
    ‍1x

    Single Item Price

    12,540 yen (including tax)

    fixed price

    11,913 yen (including tax)

  • NMN 13 Jelly

    NMN 13Jelly
    Product Details

    NMN 13 Jelly

    MULTIFUNCTIONAL GEL CONTAINING 13 INGREDIENTS INCLUDING LIPOSOMIZED NMN. COMBINED WITH THE MASSAGE TOOL "CONTOURER", IT GIVES AN UPWARD IMPRESSION.

  • 30g

    Contents
    ‍30g

    x1

    NMN ratio
    ‍1x

    Single Item Price 

    12,540 yen (including tax)

    fixed price  

    11,913 yen (including tax)

  • NMN 13 Serum for Pro

    NMN 13Serum forPro
    Product Details

    NMN 13 Serum for Pro

    Sold at clinics and salons

    RICH MODEL THAT PROVIDES SALON-LEVEL CARE AT HOME. CONTAINS TWICE AS MUCH LIPOSOMAL NMN AS THE STANDARD VERSION. RECOMMENDED FOR USE WITH A FACIAL MACHINE.

  • 30mL

    Contents
    ‍30mL

    x2

    NMN ratio
    ‍2x

    Single Item Price

    45,980 yen (including tax)

    fixed price  

    43,681 yen (including tax)

Support Items

SkinRefiner

SkinRefiner

SkinRefiner

Peeling gel that leads to clear and soft skin

5g x 4pac (4 times)

Single item price 2,980 yen (tax included)

Technology

Japan's first*1
Liposomal NMN formula
Serum & multifunctional gel

Synergistic ingredients including NMN, the main ingredient, and three types of human stem cell culture fluid are allliposomized*2.
Reaches Deeper*3 13 ingredients work omnidirectionally on the sleeping beauty skin switch to lead to glowing skin full of freshness.

*1 Survey title: "Survey on NMN Cosmetics" (TPC Marketing Research Co., Ltd.); survey targets: 1. NMN-based cosmetics listed on "@cosme," 2. NMN-based cosmetics sold on Rakuten Ichiba, Amazon, and Yahoo! 3. Cosmetics containing NMN sold through other MLM channels.
*2 Excluding dimethylaminoethanol tartrate (DMAE) and allantoin. *3 To stratum corneum

NMN 13 Series Product Images

Boosting Beauty Benefits
Liposome Technology

This is a technology that ensures the delivery of beauty ingredients to the skin by trapping them in multi-layered capsules made of phospholipids, which have a high affinity with the human skin.
Liposomization enables some easily degraded beauty ingredients to penetrate* into the skin in their freshly blended state, making it possible for the ingredients to be more appealing to the skin.

* Down to the stratum corneum

Hydrophilic part Active ingredient Hydrophobic part
NMN 13 Serum forPro
Take a closer look

13 beauty ingredients approach
glowing, radiant skin
"All-Effects Formulation®"

To bring out the full appeal of NMN, three types of human stem cell culture fluid*, seven types of peptides**, and two types of supportive ingredients are combined. The exquisite combination of 13 ingredients, including NMN based on the latest research, is the unique "All-Effects Formulation®"** of the NMN 13 series. It supports the steps to younger-looking skin.

** Human bone marrow stem cell acclimatized culture medium (skin conditioning agent), human fibroblast acclimatized culture medium (skin conditioning agent), human amniotic fluid cell acclimatized culture medium (skin conditioning agent)** Nicotinoyl hexapeptide 44 (skin protective agent), synthetic human recombinant polypeptide 31 (skin コンディショニング剤)、ヒト遺伝子組換ポリペプチドー67(皮膚コンディショニング剤)、ヒト遺伝子組換ポリペプチドー66(皮膚コンディショニング剤)、ヒト遺伝子組換オリゴペプチドー1(皮膚コンディショニング剤)、合成ヒト遺伝子組換ポリペプチドー64(皮膚 conditioning agent), Synthetic human recombinant polypeptide 16 (skin protective agent)
*All Effects Formulation® is a registered trademark of Nordeste. (Multi-functional approach to skin conditioning, skin firming, supplementing and maintaining skin moisture and oil, maintaining skin flexibility, giving skin elasticity, etc.)

Hydrophilic part Beauty ingredient Hydrophobic part
NMN 13 Jelly Contourer

EXPECTATIONS FOR NMN SKIN

NMN is also very well absorbed into the skin*, and research has shown** that when NMN solution is applied to the skin, NMN is 100 times higher and coenzymes are 4 times higher. Enjoy the NMN experience from your skin.

** Down to the stratum corneum** [Reference] Authors: Kenyuki Hattori (Keio Univ.), Ryohei Aoyagi (Keio Univ.), Akira Date (P&G Japan), Yoshihiro Abe (Keio Univ.), Etsuomi Tamura (Keio Univ.). "Effect of nicotinic acid amide mononucleotide (NMN), a precursor of NAD biosynthesis, on the differentiation of human skin epidermis," Article. 2013

13 Ingredients

NMN 13 Serum" and "NMN 13 Gelée" are the first liposomalized products in Japan*. Liposomalized peptides rich in amino acids and stem cell culture fluid extract, which continues to attract attention in the world of beauty science, are among the 13 ingredients that provide firm support for your skin.

* Survey title: "Survey on NMN Cosmetics" (surveyed by TPC Marketing Research Co., Ltd.) - Targets of the survey: 1. NMN-based cosmetics listed on "@cosme" 2. NMN-based cosmetics sold on "Rakuten Ichiba," "Amazon" and "Yahoo! Cosmetics containing NMN sold on "Rakuten Ichiba", "Amazon", and "Yahoo! Shopping" 3. Cosmetics containing NMN sold through other MLM channels.
** Excluding dimethylaminoethanol tartrate (DMAE) and allantoin
.

NMN

A rare ingredient that is gaining attention as a key to anti-aging care*.  *Age-appropriate care

1NMN [ nicotinamide mononucleotide ] (Moisturizer)

Gene-like" bio-based peptides

Human-derived peptides that support skin conditioning and skin beautification.

2 Human recombinant polypeptide-66 (skin conditioning agent)

3 Human recombinant polypeptide-67 (skin conditioning agent)

4 Nicotinoyl hexapeptide-44 [propyn] (skin protectant)

5 Synthetic human recombinant polypeptide-64 [aquaporin] (skin conditioning agent)

6 Human recombinant polypeptide-1 (skin conditioning agent)

7 Synthetic human recombinant polypeptide-16 (skin protectant)

8 Synthetic human recombinant polypeptide-31 (skin conditioning agent)

Human stem cell acclimatization culture medium

Human-derived with high affinity to skin. Luxurious rare ingredients used in the field of beauty science.

9 Human amniotic fluid cell culture medium (skin conditioning agent)

10 Human bone marrow stem cell acculturation medium (skin conditioning agent)

11 Human fibroblast acculturation medium (skin conditioning agent)

Synergy Components

IT MAXIMIZES THE ATTRACTIVENESS OF NMN AND BRINGS ABOUT A SYNERGISTIC EFFECT.

12 Dimethylaminoethanol tartrate [DMAE] (emollient)

13 Allantoin (skin conditioning agent)

Quality
Management

Quality Assurance System
Pursuit of Safety and Results

WE AT ABE YOANDO PHARMACEUTICALS CONDUCT VARIOUS INSPECTIONS AND TESTS TO ENSURE THAT WE ALWAYS DELIVER THE BEST NMN. WE WILL CONTINUE TO REDUCE EACH AND EVERY POSSIBLE RISK FROM THE TIME OF DELIVERY UNTIL AFTERWARDS.

Take a closer look

raw materials

USES HIGH-PURITY 99.9%* NMN


manufacture

Special "low-toxin manufacturing method" ensures safety of intravenous drug formulation standards.


IN-HOUSE PRODUCTION OF "HEAT-RESISTANT" NMN RAW MATERIALS

MANUFACTURED IN A PLANT THAT MEETS GQP, GVP, AND W STANDARDS

examination

Perform lot-by-lot raw material authenticity testing


Safety inspections conducted (acute toxicity testing, radioactivity testing)


Story

Based on the latest research
‍Aging Care Technology ,true beauty bloom s.

IN THE COURSE OF ABE YOANDO PHARMACEUTICAL'S DAY AND NIGHT RESEARCH, WE DISCOVERED THAT TO EFFECTIVELY TREAT AGING, IT IS NECESSARY TO ATTACK SEVEN TARGETS AT THE SAME TIME. THE "NMN13 SERIES" IS A SKINCARE LINE DEVELOPED BASED ON THIS RESEARCH AND THEORY AND EQUIPPED WITH HUMAN SKIN-FRIENDLY TECHNOLOGY.

Take a closer look

Developer's Thoughts

The development of the NMN serum began when we first encountered NMN and fell in love with its wonderful properties.
NMN is wonderful when taken, but when we learned that it also has a positive effect when applied to the skin, we repeated trial and error in order to perfect it as a skincare product at any cost.
Since we use high-quality NMN raw materials, we were also particular about the support ingredients surrounding NMN.
We have created an "All-Effect Formulation®" serum by exquisitely blending rare human amniotic stem cell purified culture fluid, seven types of peptides, and other ingredients unique to our company, so that you can fully experience the appeal of NMN.
We hope you will experience it for yourself.

Seven free" products that are designed with your skin in mind.

We want to provide a formulation that is easy on your skin because you use it every day. With this in mind, we do not use parabens, mineral oil, synthetic colorants, synthetic fragrances, talc, silicone, or vergaptene.

How to use

treatment

TO FULLY APPRECIATE THE APPEAL OF 13 KEY INGREDIENTS, INCLUDING JAPAN'S FIRST LIPOSOMAL NMN, HUMAN STEM CELL CULTURE FLUID, FUNCTIONAL PEPTIDES, AND MORE. WE WILL TELL YOU HOW TO USE THEM TO MAXIMIZE THE APPEAL OF YOUR SKIN.

Take a closer look
Customer
Voice

Customer Testimonials

FAQ

Frequently Asked Questions

Q

What is the order of use when combined with other skin care products?


Q

Can it be used on sensitive skin?

Q

Is there a smell?

Q

What is the difference between NMN13 Serum and NMN13 Serum forPro?

Q

CAN NMN13 SERUM BE USED BY MIDDLE AND HIGH SCHOOL CHILDREN AND MEN?

Q

I would like to know what people who have actually used the product think about it.